In my experience, Tuesday through Thursday is best, with Tuesday/Wednesday being better than Thursday.  On Mondays, people’s inboxes are too full from the weekend and they’re overwhelmed with email, they need to dig into work, etc.  Fridays, people are thinking about the weekend.

However, it also can depend on the email content.  If you’re marketing an entertainment product, for example, sometimes it can perform better on weekends since weekdays are less about leisure.  There may be fewer email “opens” on weekends but better response for non-productivity product content emails.  At the end of the day the best way to know for sure what’s best for your particular product is of course to test the different dates for the same offer and sent to the same type of users (comparing apples to apples across different days).

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